Antimicrobial Resistance (AMR)

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AMR poses one of the greatest threats to global health, with devastating consequences for humans and animals alike. As veterinary industry professionals, we are at the forefront of combating this challenge by safeguarding the effectiveness of antimicrobials. This resource hub is designed to support UK vets in tackling AMR, providing practical tools, educational content, and guidance on antimicrobial classifications.

AMR

Why is AMR a Critical Concern?

AMR occurs when microorganisms, like bacteria, evolve to resist the drugs designed to kill them, rendering treatments ineffective. Alarmingly:

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1.27 million deaths globally in 2019 were directly attributable to AMR, with animals and humans sharing this burden of resistance. (1)

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The economic impact of AMR is projected to cost £78 trillion by 2050 if current trends continue.(2)

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In the UK, antimicrobial use in animals has decreased by 52% since 2014, yet resistance remains a persistent challenge.(3)

As stewards of animal health veterinary professionals play a pivotal role in promoting responsible antimicrobial use to curb this growing threat.

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Cytology Wall Chart

Ear Cytology Method and Results Wall Chart: Display this wall chart and elevate your practices’ cytology proficiency, with this comprehensive guide to ear cytology sampling. Gain confidence in microscopy techniques to ensure precise and accurate diagnoses.

Implementing cytology is a crucial step in promoting antimicrobial stewardship by enabling targeted treatment decisions and reducing unnecessary antimicrobial use.

The Antimicrobial Advice Ad hoc Expert Group (AMEG) started classifying antibiotics A-D in 2019. This system plays a vital role in helping veterinary professionals identify high-risk antibiotics that could impact animal, human, and environmental health, aligning with the global ‘One Health’ initiative.

To further assist in responsible prescribing, we’ve integrated the AMEG Classification into all Bova UK antibiotic product labels. These clear visual indicators empower you to make informed decisions quickly, promoting the appropriate level of caution when prescribing antimicrobials. This ensures the best outcomes for your patients while actively mitigating the risks of antimicrobial resistance.

The AMEG system classifies antimicrobials into four distinct groups:

Head to the European Medicines Agency website to read more about the scientific advice on the categorisation of antibiotics you are prescribing to patients under your care: Categorisation of antibiotics used in animals promotes responsible use to protect public and animal health | European Medicines Agency (EMA)

Addressing AMR requires more than reducing antimicrobial use; it also calls for better education on selecting the correct antimicrobials and understanding when and how to use them responsibly.

As part of our sustainability strategy, we have established a clear goal to educate and support veterinary professionals and caregivers through the resources on this page. These efforts align with the United Nations Sustainable Development Goal (SDG) Target 3, which promotes global health and well-being.

Through these initiatives, we aim to foster a culture of stewardship, ensuring veterinary teams have the knowledge and tools needed to make informed decisions. Subsequently, we safeguard the future of veterinary medicine and protect both animal and human health.

What is antimicrobial stewardship, and why is it important in veterinary medicine?

Antimicrobial stewardship refers to the responsible use of antimicrobials to preserve their effectiveness. In veterinary medicine, it ensures that antibiotics are used appropriately to treat infections while minimising the risk of resistance developing, which protects both animal and human health.

How can I help prevent antimicrobial resistance as a pet owner?

Follow your veterinary surgeon’s instructions when giving antimicrobials to your pet, complete the prescribed course and never share or use leftover antimicrobials.

How does improper use of antimicrobials contribute to resistance?

Improper use, such as underdosing, skipping doses, or stopping treatment early, can allow microbes to survive and adapt, making them resistant to future treatments of the same type.

How does antiviral resistance happen in pets?

Similar to antibiotics, viruses can develop resistance to antivirals when the medication is misused or not given for the full recommended course.

Can worms in pets develop resistance to deworming medications?

Yes, overusing or underdosing dewormers can lead to worms developing resistance, making the medication less effective over time.

What role do veterinary surgeons play in combating antimicrobial resistance?

Veterinary surgeons diagnose infections, prescribe the right antibiotic when necessary, and educate pet owners about proper use, helping to reduce the misuse and overuse of these medications.

Why is it important to complete an antibiotic course, even if my pet seems better?

Stopping antibiotics too soon can leave surviving bacteria in the body, which may develop resistance and cause a recurrence of the infection.

How do diagnostic tests help guide appropriate antibiotic use in animals?

Tests like bacterial culture and sensitivity testing identify the exact cause of an infection and determine the most effective antibiotic, reducing unnecessary or ineffective treatments.

Why should we test worm burdens in horses before deworming?

Testing for worm burdens, such as through faecal egg counts, helps determine the type and level of worm infestation in horses. This ensures the correct dewormer is used and avoids unnecessary treatments, which can lead to drug resistance, making treatments less effective in the future.

Can antimicrobial resistance spread between animals and humans?

Yes, resistant bacteria can spread between animals and humans through direct contact, the environment, or the food chain, emphasising the importance of responsible antibiotic use.

What are the risks of using leftover antibiotics for my pet?

Leftover antibiotics may not be the right type, dose, or duration for your pet’s current condition, leading to treatment failure or resistance.

How can hygiene and biosecurity practices reduce the need for antibiotics?

Proper hygiene, handwashing and biosecurity measures prevent the spread of infections, reducing the need for antibiotics in both animals and humans.

Why is proper disposal of unused antimicrobials important?

Improper disposal can harm the environment and contribute to resistance. Follow your veterinary surgeon’s guidance for safe disposal.

What is the difference between broad-spectrum and narrow-spectrum antibiotics?

Broad-spectrum antibiotics target a wide range of bacteria, while narrow-spectrum antibiotics are effective against specific bacteria. Narrow-spectrum antibiotics are preferred when the cause of infection is known to reduce resistance risk.

Are there vaccines available to prevent infections that often require antibiotics?

Yes, vaccines are available for many bacterial infections, such as leptospirosis in dogs, helping reduce the need for antibiotics.

Why are new antibiotics for animals being developed so slowly?

Developing new antibiotics is costly and time-consuming, with strict regulatory requirements. Pharmaceutical companies often focus on alternatives and stewardship to extend the life of existing antibiotics.

What is the global impact of antimicrobial resistance in veterinary medicine?

AMR threatens animal health, food security, and livelihoods worldwide. It increases treatment costs, reduces effective options, and has implications for human health due to shared bacterial strains.

What is the One Health approach, and how does it address AMR?

The One Health approach recognises the interconnected health of people, animals, and the environment. It promotes collaborative efforts across sectors to combat AMR by improving stewardship, surveillance, and infection prevention.

What resources are available for pet owners to learn more about AMR?

Resources include your veterinary surgeon, trusted veterinary websites, organisations like the World Health Organisation (WHO) and World Organisation for Animal Health (WOAH), and public awareness campaigns during World Antimicrobial Awareness Week.

Antimicrobial resistance

Antimicrobial resistance – WOAH – World Organisation for Animal HealthAMR Hub – RCVS Knowledge