Sustainable control practices for equine tapeworm (2024)
Overview
Attendees will be cognizant of the following information by the end of the webinar:
• Horses that graze can be infected by the tapeworm, Anoplocephala perfoliata
•Equine tapeworm has an indirect lifecycle involving an oribatid/pasture mite intermediate host
• Adult tapeworms are hermaphrodite and intermittently release segments containing eggs
• The adult worms are found in caecum and, particularly, the ileo-caeco-colic junction
•Most horses have low burdens of tapeworm
• The prevalence of tapeworm varies between different groups of horses
• A main risk factor for tapeworm infection is access to pasture• Horses are infected year-round with tapeworm
• Equine tapeworm can cause colic
• The level of burden correlates with the risk of colic
• Burdens of 20 tapeworms and over have been demonstrated as pathogenic
• Serum IgG(T) levels to tapeworm excretory/secretory (ES) antigens of 12/13 kDa correlate with infection intensity
• Serum IgG(T) to 12/13 kDa ES antigens correlates with risk of colic
• Anthelmintic resistance in tapeworm to praziquantel and pyrantel was reported in 2023
• Faecal egg count tests have poor sensitivity for detecting tapeworm infection due to intermittent release of egg-containing proglottids and burdens comprising a proportion immature/sterile worms
• Serum and saliva tests that measure IgG(T) to tapeworm 12/13 kDa ES antigens can be used to diagnose infection to inform anthelmintic treatments and as an aid to diagnosis in colic cases
• Horses can be assessed in theTapeworm Blood Test 4 months after their last treatment
• Horses can be assessed in the EquiSal Tapeworm Saliva Test 3 months after their last treatment • Tapeworm antibody tests do not provide a value for exact numbers of worms but generate a score that provides a low, borderline or moderate/high tapeworm diagnosis. Treatment is recommended for horses that report a result as borderline or moderate/high
• Use of the EquiSal Tapeworm Saliva Test has led to considerable reductions in anti-tapeworm treatments in the UK, with 2 out of 3 horses tested not requiring treatment based on test results
• Control of tapeworm should combine good pasture management (low stocking density, removal of dung at least twice a week) with diagnostic testing to inform treatment decisions
• Anthelmintics licensed to treat equine tapeworm in the UK are pyrantel embonate (at twice the dose used for nematode species) and praziquantel (in combination with a macrocyclic lactone or as a single-active extemporaneous formulation that can only be prescribed by a veterinary surgeon).
Presenters
Professor Jacqui Matthews, BVMS PhD FRSB FRSE FRCVS
Prof. Jacqui Matthews qualified as a veterinary surgeon before completing a PhD in parasite immunology at the University of Glasgow. After her PhD, she worked in academia for >25 years, leading interdisciplinary research projects for which she received >£13M competitive funding. Her outputs, primarily on helminth vaccines and diagnostics, include>145 peer-reviewed papers, several patents, numerous lay articles and invited plenary and stakeholder talks. In this period, Jacqui taught parasitology to undergraduates and postgraduates at Glasgow, Liverpool and Edinburgh veterinary schools, as well as being active in veterinary CPD initiatives. For many years, she was technical advisor to the Control of Worms Sustainably in Cattle industry initiative and parasitology expert on the Veterinary Products Committee. She currently sits on the Steering Group of CANTER, a cross industry initiative that seeks to promote best practice equine parasite control, and is a member of BBSRC Research Committee A and the Royal Society of Edinburgh’s STEM Research Committee. Jacqui was conferred fellowship of the Royal College of Veterinary Surgeons for meritorious contributions to knowledge in 2017 and is a fellow of the Royal Society of Edinburgh, Royal Society of Biology and is a RCVS recognized specialist in Veterinary Parasitology. One of her inventions, a blood test for equine small redworm, was commercialised by Austin Davis Biologics in 2019 and, in 2022, she moved to this company as Director of Veterinary Science, where she leads the R&D programme and works with end-users in promoting evidence-based parasite control.